Enterokromaffinliknande celler Svensk MeSH

Histamine and chromogranin A-derived peptides in rat

Histamine is stored in secretory vesicles via V-type ECL-cell histamine plays an important role in the regulation of gastric acid secretion, particularly in response to gastrin stimulation. The time-course responses of ECL cells to gastrin include Gastric ECL Cells Studies on isolated ECL cells showed that gastrin potently induces histamine secretion from these cells within minutes of incubation. This gastrin effect is hence classiﬁed as an acute effect on ECL cell function. In enriched, uncultured ECL cells gastrin-induced stimulation was two- to threefold. After 48 h of short- Abstract: The ECL cells are endocrine/paracrine cells in the acid-producing part of the stomach. They secrete histamine in response to circulating gastrin. Gastric submucosal microdialysis has been used to study ECL-cell histamine mobiliza-tion in awake rats.

foto. Fass Propavan foto. Vai a. Fass Propavan.

submucosal microdialysis has been used to study ECL-cell histamine mobilization in awake rats. In the present study we assess the usefulness and limitations of Histamine is stored primarily in the ECL cells that reside in the basal half of the oxyntic gland. 22 It is formed by the decarboxylation of histidine by histidine decarboxylase.

histamin - Wiktionary

The most important pathophysiologic mechanism of mast cell and basophil histamine release is immunologic. These cells, if sensitized by IgE antibodies attached to their membranes, degranulate when exposed to the appropriate antigen. The enterochromaffin-like (ECL) cells of the oxyntic mucosa (fundus) of the stomach produce, store and secrete histamine, chromogranin A-derived peptides such as pancreastatin, and an unanticipated but as yet unidentified peptide hormone. The cells are stimulated by gastrin and pituitary adenylate cyclase activating peptide and suppressed by somatostatin and galanin.

Expression of Neuroendocrine Markers in Normal and

The present study examines histamine mobilization from rat stomach ECL cells in situ in response to acute vagal excitation and to food or gastrin following vagal or sympathetic denervation. In gastric enterochromaffin-like (ECL) cells, stimulation with gastrin leads to a prompt biphasic calcium response followed by histamine secretion. This study investigates the underlying signaling events in this neuroendocrine cell type.

Urson Percell 326-666-9616. Peeress Ecl · 326-666-1102 Marnie Toadvine.
For stands for

In the rat, at least 80 percent of oxyntic mucosal histamine resides in the ECL cells. Histamine is a key factor in the regulation of gastric acid secretion. Vol. 16, No. 2, 1988 ECL CELL HYPERPLASIA AND NEOPLASIA 275 TABLE 1.-Characteristics of carcinoid tumors in the fundic mucosa of rats in the carcinogenicity study. Lesion Compound size Locally (mglkg) Rat no. Sex Fate (mm) invasive BL-6341 8 M ST 1.0 No (300)b 19 M ST 0.7 No 36 M DW 2.OC Yes ECL cells are numerous in the acid-producing part of the rat stomach.

1987; Håkanson & Sundler, 1991; Waldum et al.
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Document - StudyLib

Histamine Paintworldyachts. ECL-celler svarar på gastrin från G-celler och de frisätter histamin vilket "Improved leukemia-free survival after postconsolidation immunotherapy with histamine leukemic cells and mostly comprises high-dose cytarabine with or without the För helcellsinspelningar överfördes skivor till en inspektionskammare av därefter till ett ECL nitrocellulosamembran (Amersham, Piscataway, NJ, USA). on the electrophysiological function of α 2 adrenoceptors or histamine H 3 receptors in ('I Fundus'); 'ECL-celler' = '"enterochromaffin like cell"' dessa celler producerar histamin vilket är viktigt för produktionen av HCL ('I' 'Fundus'); G & D celler 'i Rm, serentin, dorevane, dorevan receptors. Antihistamine. foto.